Dr. Roli Mishra

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Dr. Roli Mishra
M.Sc., D.Phil.
Assistant Professor

Chemistry Department
University and Institute of Advanced Research
(Puri Foundation for Education in India)
Koba, Gandhinagar, Gujarat, India
Ph: +91-79-30514130
Fax: +91-79-30514110
Email :rolimishra2@gmail.com; rolimishra@iar.ac.in


Academics:

  • M. Sc. (Organic chemistry) Department of Chemistry, University of Allahabad, (2000)    
  • D. Phil. Department of Chemistry, University of Allahabad, (2006)
  • DBT Postdoctoral Fellow, Department of organic Chemistry, Indian Institute of Science, Bangalore 2006-2008
  • Research Associate: Department of Medicinal Chemistry, University of Minnesota-Twin Cities, Minneapolis USA 2010- 2011
  • Research Associate: Chemistry Department, Indian Institute of Technology, Delhi, (2012-2014)
  • Assistant Professor; University and Institute of Advanced Research, Koba, Gandhinagar - 382007. Gujarat, India.

 

Research Interests:

    • Development of Novel synthetic Methodologies.
    • Supramolecular Chemistry and Dendrimers Chemistry.
    • Peptide Synthesis.
    • Physio-Chemical properties of Ionic Liquids.
    • Development of small molecules for therapeutic uses anticancer agents, antibacterial.
    • Chemically modified oligonucleotides; its biophysical applications.
 

Research Publications:

1.Roli Mishra, Shubha Pandey, Shruti Trivedi,  Siddharth Pandey and Pramod S. Pandey Peptide-based chiral Ionic Liquids: synthesis, properties and applications.   RSC Advances, 4, 2014, 33478-33488.

2.Ramapanicker Ramesh, Roli Mishra and Srinivasan Chandrasekaran An Improved Procedure for the Synthesis of Dehydroamino Acids and Dehydropeptides from the Carbonate Derivatives of Serine and Threonine using Tetrabutylammonium Fluoride. J. Peptide Synthesis, 16(3), 2010, 123-125.

3.Subhra Prakash Chakrabarty, Ramapanicker Ramesh, Roli Mishra, Hema Balaram, Srinivasan Chandrasekaran. Development and characterization of lysine based tripeptide analogues as inhibitors of Sir2 activity. Bioorg Med Chem. 17(23), 2009, 8060-72.

4.Roli Mishra, Krishna Misra. Di(tert-butyl)[(pyren-1-yl)methoxy]silyl Chloride: Synthesis and Application in Purification of Synthetic Deoxyribonucleotides. Chem. Lett., 35(6), 2007, 768-769.

5.Shiv Kumar Dubey, Archana Pandey, Roli Mishra, Neha Kapoor, Alka Tiwari and Krishna Misra. Site directed drug delivery by non-viral mode. (Review) Ind. J. Biotech. 6(1), 2007, 159-174. (Review Article)

6.Roli Mishra, Satyendra Mishra, Krishna Misra. Synthesis and application of fluorous-tagged oligonucleotides.  Chem. Lett., 35(10), 2006, 1184-1185

7.Roli Mishra, Satyendra Mishra, Vishnu Diwedi, Krishna Misra. A strategy for selective N-acylation of purine and pyrimidine bases of deoxy and ribo nucleosides. Nucleic Acids Symp. Ser., (50), 2006, 7-8. 

8.Satyendra Mishra, Snehlata Tripathi, Roli Mishra and Krishna Misra. Synthesis, Characterization and Antiproliferative activity of a Novel Anticancer Prodrug Designed to Target Telomerase Sequence. Ind. J. Chem., 44B (10), 2005, 2582-25-88. 

9.Satyendra Mishra, Upama Narain, Roli Mishra and Krishna Misra. Design, Development and Synthesis of Mixed Bioconjugates of Piperic Acid-Glycine, Curcumin-Glycine/Alanine and Curcumin–Glycine-Piperic Acid and their Antibacterial and Antifungal Properties. Bioorg. Med. Chem., 13, 2005, 1477–1486..

 

Symposia / Conferences/ Work shop attended:

1.32nd National Medicinal Chemistry at University of Minnesota, Twin Cities Campus in Minneapolis, June 6-9, 2010. (Attended)

2.Satyendra Mishra, Roli Mishra, Upama Narain and Krishna Misra Design, development and synthesis of curcumin bioconjugates and their antibacterial and antifungal activity. 228th ACS National meeting in Philadelphia, p.130, MEDI 209.

3.Roli Mishra and Krishna Misra. Cost effective procedure for the synthesis of of selective N- acylation of Deoxynucleosides, 74th Annual Session of National Academy of Sciences, India Dec.2-4, 2004. (Speaker)

4.Satyendra Mishra, Upma Narain, Roli Mishra Shiv Kumar Dubey and Krishna Misra Design and development of curcumin-piperic acid bioconjugates and their antibacterial and antifungal activity. Biotech Research Society of India, Jalgaon,   India, Nov 25-27, 2004.

5.Roli Mishra, Satyendra Mishra and Krishna Misra, An Improved procedure for synthesis of oligonucleotides, CONIAPS -VI, Gorkhapur February 6-8 2004. (Speaker)

6.Neha Kapoor, Roli Mishra and Krishna Misra. Effect of Some Azo and   Antraquinone Dyes on Melanin Synthesis, 91st Session of Indian Science Congress Chandigarh,1 –7 Jan 2004.

 

Book Chapter published:

1. Published a chapter entitled “Design of a biocompatible nanocomposite particulate and drug delivery system” in a Book “Recent Developments in Bio-Nanocomposites for Biomedical Applications” of  Nova Science Publication ISBN: 978-1-61761-008-0.

 

Fellowships:

  • DBT-Postdoctoral fellowship from Department of Biotechnology, Government ofIndia (January 2006-October 2008)
  • Research Associate fellowship from National Academy of Science, Allahabad).

 

Memberships:

  • Life Member of Chemical Research Society of India
  • Life Member of Indian Science Congress Association